Hi, Ajay... As you said..you have relapses of psoriasis on lower extremities..You have tried many treatment,without good response..right? You should be aware of the pathology of the disease.Psoriasis is a chronic relapsing and autoimmune disease. You may be having scaly plaques on various parts of the body , even on the scalp. There may be dryness of skin,which might cause itching.Exact cause is not known. Genetic tendency,autoimmunitity,stress, dry wheather...etc may be responsible for precipitation and exacerbation of the disease. I advise you to consult dermatologist personally for firm diagnosis and perfect treatment. Avoid anxiety and tension related with your disease. I usually recommend cap acitretin 10 mg twice a day along with methotraxate 15 mg weekly in three devided doses 12 hourly. This may be taken for long time till good response. Blood tests may be done to monitor the treatment. Apply mild steroid cream or calcipotriol oint on the lesions. If you have scalp psoriasis,tar shampoo may be done. You may apply moisturiser to improve the skin texture. Avoid soap bath for few weeks.Avoid stress and worries as that might worsen psoriasis. Have pateince for recovery. You take treatment under observation of dermatologist.I hope you got my answer. Thanks. Dr. Ilyas Patel MD