i have positive ANA test. I have swollen hands, stiff muscles (rigid not very flexible), i have tighness of muscles in face as well and have had some hair loss in arm pits and eyebrows. i am 37 year old male and have had this for about 2 years. Have seen numerous Doctors who ruled out heart, liver, kidneys as a cause. I am finally seeing rheumatologist. I had a positive LAC and now it has gone negative. I was on plaquenil but it caused blurred vision. now just taking ibuprofen and tylenol as needed. Still get bad stomach muscle cramps and have swelling everyday in hands and feet. We have not been able to isolate what i have. Lupus is negative as well.