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Suggest Treatment For Lung Infection Due To TB
Hello Doctor,
My brother is 32 and he was diagnosed with TB about a month back and Doctors say that it's in an advanced stage with more than 1/3 of 1 lung affected. He is also an epiliptic patient from his childhood and currently, he is on Carbamaprazine (1000 Mg). He was immediately reccommended the standard TB drug regime - INH, Refampicin, Ethnambutol, and Pyrazinamide. After a week of intake of the drugs, he had epileptic attack and severe vomiting and was put only on drips as food intake was impossible. His lever was also seriously damaged with Serum beryllium greater than 1 from LFT. This could be becuase of "interaction" of the drugs. Then, doctors stopped INH, Refampicin (RCIN) and started another Regimen with Streptomycin and Ethnambutol and started introducing INH and then, Refampicin in an incremental way. But each time they tried to up the dose, lever was getting affected and also, due to interaction with Carbamaprazine, levels in blood were either increasing or decreasing. Recently, he also had a rupture in the rectum and there was a lot of blood in his stool. I do not see any improvement currently and need advice on a good Hospital in Bangalore (preferably) or Chennai or Hyderabad where the treatment can be done effectively.
Thanks a lot!
My brother is 32 and he was diagnosed with TB about a month back and Doctors say that it's in an advanced stage with more than 1/3 of 1 lung affected. He is also an epiliptic patient from his childhood and currently, he is on Carbamaprazine (1000 Mg). He was immediately reccommended the standard TB drug regime - INH, Refampicin, Ethnambutol, and Pyrazinamide. After a week of intake of the drugs, he had epileptic attack and severe vomiting and was put only on drips as food intake was impossible. His lever was also seriously damaged with Serum beryllium greater than 1 from LFT. This could be becuase of "interaction" of the drugs. Then, doctors stopped INH, Refampicin (RCIN) and started another Regimen with Streptomycin and Ethnambutol and started introducing INH and then, Refampicin in an incremental way. But each time they tried to up the dose, lever was getting affected and also, due to interaction with Carbamaprazine, levels in blood were either increasing or decreasing. Recently, he also had a rupture in the rectum and there was a lot of blood in his stool. I do not see any improvement currently and need advice on a good Hospital in Bangalore (preferably) or Chennai or Hyderabad where the treatment can be done effectively.
Thanks a lot!
Sat, 5 Jul 2014
Hello
After going through your brother's history of illness I want to tell you somethings as . When such patient visit my clinic I at once start intravenous infusion with heavy doses of ranitidine ( in I/V infusion ) . Since your brother weight must be less than 50 kg start forecox( RIFAMPICIN 225 mg , isonizide 150 mg , ethambutol 400 mg , pyrazinamide 750 mg ) one tablet / day after 2-3 hours of meal .
Add PANTACLOC_D once or twice in day .
Carbamazepine can be given after 2 hour gap.
Also add some LIVER enzyme in higher doses .
No doubt your brother is weak in general condition but his condition is not so serious , once drugs will adjust his condition will improve.
There are so many the best quality hospital in Chenai or banagalore , so consult a primary care physician and get his opinion , else consult a PULMONOLOGIST and get his opinion.
Good luck.
After going through your brother's history of illness I want to tell you somethings as . When such patient visit my clinic I at once start intravenous infusion with heavy doses of ranitidine ( in I/V infusion ) . Since your brother weight must be less than 50 kg start forecox( RIFAMPICIN 225 mg , isonizide 150 mg , ethambutol 400 mg , pyrazinamide 750 mg ) one tablet / day after 2-3 hours of meal .
Add PANTACLOC_D once or twice in day .
Carbamazepine can be given after 2 hour gap.
Also add some LIVER enzyme in higher doses .
No doubt your brother is weak in general condition but his condition is not so serious , once drugs will adjust his condition will improve.
There are so many the best quality hospital in Chenai or banagalore , so consult a primary care physician and get his opinion , else consult a PULMONOLOGIST and get his opinion.
Good luck.
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