Hi Dear XXX! I have gone through your questions and I understand your concern. According to what you describe the symptoms may be caused by lumbar facet syndrom. The joint that are between the vertebre L4-L5 compress your nerves that goes through tham and cause you numbness ,pain and tingling.Is especially in your right feet cause the right joint is more damaged. I would say that the Medial branch block is a good treatment while you are experiencing nerve damage , its local anesthesia so the chance to affect your all body and to interact with your depression medicine is very low . I would suggest to follow these advice : -Try to have a good posture of the body , exp.: stay straight when you sit in the chair , avoid any extension or oblique extension of your body or any position that worsen the pain or symptoms . Use superficial heaat Take ibuprofen or topical antiimflamator . Wish these help . If you have any other questions please feel free to ask me .