Hi there, thanks for puting your faith in HCM. I would rather appreciate you for a more concise and detailed note of your history. However, I would have preferred to know the bilirubin levels though, as well as any associated symptoms like itching, decreased appetite or vomiting you experience along with increased levels of bilirubin as jaundice is a symptom which is basically the rise of the yellowish pigments (bilirubin in your body) which are normally converted by liver in soluble forms and excreted into your gut to be excreted out of your body with the stools. The first such incidence of its rise which you experienced in your neonatal life iwhich resolved itself is a type called physiological jaundice and it is not considered to be a disease so you need not to worry about that, but the second incidence in your adolesence might be because of
acute hepatitis which in majority of cases is viral. but its recurrence is a bigger concern for me as it needs a detailed evaluation to rule out any other cause of
chronic liver disease. Though such higher levels of ALT are usually present in
Hepatitis A or E which resolves by itself between 1-2 weeks approximately. Your GGT levels indicate around 5 times of the normal levels of your age group which is suggestive of
intrahepatic cholestasis or inflammatory hepatitis again favoring an acute inflammatory cause which is likely viral mostly and is water born disease with self remission. If these levels were as higher as 10-30 times we would have suspected any obstruction of bilirubin outflow (aka biliary tract diseases) which are unlikely in your case. Also that there are some diseases which interfere in conversion of insoluble blirubin into soluble ones or in the excretion inside liver cells due to enzyme deficiencies, which when present or detected in adolescence or afterwards is Gilberts disease in most of the cases which needs monitoring only along with symptomatic care with no long term treatment need. If i were your physician i would have ordered viral serologies for hepatitis, along with an
ultrasound for liver size and structure as well as outflow tracts from liver and their patency, along with an albumin globulin ratios. I would also have been interested to know synthetic functions of your liver by monitoring INR to see for any need of Vitamin K supplementation. The ideal treatment is rest, Fluids, Hydration, anti Emetics and motility agents like
domperidone for vomitings and associated symptoms. Also that if you were experiencing and symptoms of itching, decreased intake, severe vomitings or
drowsiness i would have wanted to start bile binding drugs like chlestyramines and ursodecholic acids to make the extra bilirubin soluble and ready for excretion. If you experience any active bleeding or black stools, immediately consult a tertiary care hospital. I were you i would have arranged consultation with a gastro-entrologist too.