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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For Hot Flashes And Nausea With High Liver Enzymes

I stopped taking Letrozole 2 weeks ago. I had been taking it since Feb 2014. In April, my Alkaline phosphatase was 71 U/L. Today, it was 125 U/L, my AST/SGOT is 1450 U/L and ALT/SGPT is 682. I have had multiple symptoms-muscle aches in legs, arm, shoulders to the point my gait was altered and I started limping, cold flashes sometimes with hot flashes and last night pain between my breasts, a back ache and nausea. I had a complete workup with CT on my lungs, Chest x-ray, Ultrasound of my liver, right kidney and large bile duck and EKG monitoring overnight. Everything was negative and the medical team at our local hospital diagnosed the adverse drug reaction. How long before the Letrozole is out of my system and is there anyway to predict how long b/4 my liver tests are more normal? I am 67 with a history of breast CA, both breasts removed. Drs. plan to monitor my liver tests and I am calling the oncologist tomorrow am. Many thanks
Mon, 27 Apr 2015
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General & Family Physician,  's  Response
Welcome to Health care magic. Thank you for posting your question.
I can understand your concern.

I can understand that you are very anxious about your health.
Jaundice can be due to many causes like Hepatitis , gall stone disease(acute cholecystitis) , pancreatitis - to name a few.
Mere dietary adjustments often cannot cure it.
It would have been great had I examine you on my own.
You need to undergo a few tests to find out the exact cause.



I would suggest you to

- Avoid oily, fatty food
- Drink plenty of fluid
- Do not smoke.Stop alcohol
- Have a BLAND DIET .
- Repeat the abdominal ultrasound, Complete blood count , Liver function test, platelets, urea, creatinine , electrolytes done - This will help in the diagnosis

Visit a gastro-enterologist . He or she can examine you and correlate clinically. Consult with your oncologist.


Do not worry.

Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.

Wishing you good health.
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Suggest Treatment For Hot Flashes And Nausea With High Liver Enzymes

Welcome to Health care magic. Thank you for posting your question. I can understand your concern. I can understand that you are very anxious about your health. Jaundice can be due to many causes like Hepatitis , gall stone disease(acute cholecystitis) , pancreatitis - to name a few. Mere dietary adjustments often cannot cure it. It would have been great had I examine you on my own. You need to undergo a few tests to find out the exact cause. I would suggest you to - Avoid oily, fatty food - Drink plenty of fluid - Do not smoke.Stop alcohol - Have a BLAND DIET . - Repeat the abdominal ultrasound, Complete blood count , Liver function test, platelets, urea, creatinine , electrolytes done - This will help in the diagnosis Visit a gastro-enterologist . He or she can examine you and correlate clinically. Consult with your oncologist. Do not worry. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Wishing you good health.