Hi Dear !! Thanks for your query to HCM .
Read and reviewed your query and health concerns.
You seems to suffer from -
Methotrexate induced bonemarrow
depression with secondary
opportunistic infection causing sever fatigue.
Bowel movements could be laborious task for those on Methotrexate and hence needs to supported with high doses of Bplex with
Folic Acid, to prevent
bone marrow depression side effect in you.
Shaking from cold is due to Secondary bacteremia-caused after defecation due to mucosal erosions in cases with Methotrexate.
Physicians Consults and needful treatment is needed.
Hope this would help you to plan further care of this complex illness of yours.
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Good Day!!
Wishing Good Healthy Life in time to come!!
Dr.Savaskar M.N.
Senior Surgical Specialist
M.S.Genl-CVTS