Hello. Thanks for writing to us at healthcaremagic I will keep a possibility of palmoplantar keratoderma. This condition is due to extreme dryness of the skin of the palms and soles, manifesting as cracking and fissuring. The condition is more commonly seen in atopics; those who already have an underlying dry skin. Frequent washing with soaps exacerbates the condition further. Therefore, soaps and detergent use should be restricted to the minimum. Urea and ammonium lactate based moisturizers are quite good for extremely dry and cracked, fissured skin in this condition. They are keratolytics i.e exfoliate dead skin. They also trap moisture from the atmosphere and lock it into the skin(hygroscopic agents) Apart from using moisturizers, I also usually recommend my patients to use a potent topical steroid e.g clobetasol propionate, twice daily. Steroids are antinflammatory and help heal the cracks and fissures faster along with moisturizers. The condition may recur. Regular use of a moisturizer frequently and each time after hand washing is recommended. Skin biopsy would be able to reveal whether it is psoriasis. Regards