There are a lot of factors that go into deciding the best treatment for patients with severe aortic stenosis, especially when it is causing heart failure. The most immediate step is putting those patients on heart failure medications, which may include a beta-blocker like metoprolol, an ACE-inhibitor like lisinopril, and sometimes a water pill like Lasix. Afterwards, the most important step becomes treating the underlying cause, which in her case seems to be her aortic stenosis. When assessing the severity of the aortic stenosis, the cardiologist will perform an Echocardiogram to determine the cross-sectional area of the opening that the aortic valve allows. In your grandmother s case, it seems to be Transcatheter Aortic valve replacement (TAVR) is a much less invansive procedure than a surgical aortic valve replacement (SAVR). TAVR is generally associated with lower rates of major bleeding and atrial fibrillation, but higher rates of short-term aortic valve reintervention, pacemaker implantation, and aortic regurgitation compared with SAVR. In people your grandmother s age, the benefits of a TAVR outweigh the associated risks since she will likely not live long enough to require a new one (unfortunate truth). This is still an invasive procedure and would require your grandmother to feel like it s worth the extra time it would buy for her. Chelation therapy will not help her physically. It may even cause more harm, however perhaps emotionally it may make her feel better. These are decisions you all will need to make as a family