Hello! Thank you for asking on HCM! I read your question carefully and understand your concern. I would like to explain that both topamax and lamotrigine are antiepileptic drugs, usually used for the treatment of seizures and migraine prevention. But they have also another effect, which is mood stabilizer. Lamotrigine is more famous for this effect than topamax. Other antiepileptics very effective in your medical condition are carbamazepine and valproate, although they have more side effects than topiramate and lamotrigine. Regarding ciprolex, it is an antidepressant, helpful in treating negative signs of bipolar disorder (depression, lack of hope, etc). If your condition has not got better with this therapy, I would recommend consulting with your psychiatrist to consider the possibility to switch into another antiepileptic (like valproate or carbamazepine), or start Lithium therapy, which is very effective in bipolar disorder if no contraindications and well tolerated. Hope to have been of help! Best wishes, Dr. Aida