Hello, Welcome to healthcare magic. Acanthosis nigricans could be associated with obesity and is also a marker for diabetes. I understand your frustration. You could continue venusia cream in the morning. After using flutivate cream for 3 weeks, use a cream containing .0.25% Tretinoin at bedtime on the neck. Do not use this on other areas like underarms and groins as it can irritate the delicate skin there. You could get retinol peels or yellow peels done by a dermatologist. You should try to lose weight as this is the major contributing factor for the darkness. Be positive and motivated and you will do well. Hope this helps you. Take care.