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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest Treatment For PLEVA Disease

I have just been diagnosed with Pleva. Maybe two months before I started getting sores I had a living arrangement change and now share a room with my cat and litter box. the cat is always on my bed and at a point was carrying cat litter onto my bed. I ve realized now that he also has fleas. Could this all be related?
Tue, 3 May 2016
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General & Family Physician 's  Response
Hi,
Thanks for posting in HCM.
PELVA is 'pityriasis lichenoides et varioliformis acuta'. It is a rare cutaneous disorder of unknown etiology.
The cause is not yet known but 3 major theories exist:
1. An inflammatory reaction triggered by infectious agents
2. A relatively benign form of T-cell lymphoproliferative disorder
3. An immune-complex-mediated hypersensitivity vasculitis
Treatment for this disorder include:
1. Local wound care - Infected lesions are to be treated with topical Mupirocin cream and sterile dressing changes twice daily.
2. Topical steroids can be applied to reduce irritation.
3. Topical immunomodulator crewams like Tacrolimus ointment to be applied twice daily.
4. A course of oral antibiotics like erythromycin or doxycycline needs to be taken.
5. Exposure to sunlight may help to resolve lesions.
6. Phototherapy with artificial ultraviolet radiation treatment using UVB or PUVA can be used as a second line therapy.
Hope the information provided would be helpful.
All the best.
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Suggest Treatment For PLEVA Disease

Hi, Thanks for posting in HCM. PELVA is pityriasis lichenoides et varioliformis acuta . It is a rare cutaneous disorder of unknown etiology. The cause is not yet known but 3 major theories exist: 1. An inflammatory reaction triggered by infectious agents 2. A relatively benign form of T-cell lymphoproliferative disorder 3. An immune-complex-mediated hypersensitivity vasculitis Treatment for this disorder include: 1. Local wound care - Infected lesions are to be treated with topical Mupirocin cream and sterile dressing changes twice daily. 2. Topical steroids can be applied to reduce irritation. 3. Topical immunomodulator crewams like Tacrolimus ointment to be applied twice daily. 4. A course of oral antibiotics like erythromycin or doxycycline needs to be taken. 5. Exposure to sunlight may help to resolve lesions. 6. Phototherapy with artificial ultraviolet radiation treatment using UVB or PUVA can be used as a second line therapy. Hope the information provided would be helpful. All the best.