Hi, Chronic kidney disease affects most people with diabetes in those having the condition for more than 10 - 15 years. The early stages cause an elevated glomerular filtration rate with enlarged kidneys, but the principal feature of diabetic nephropathy is proteinuria. This develops insidiously, starting as intermittent microalbuminuria before progressing to constant proteinuria and occasionally nephrotic syndrome. Diabetes also affects the nerves and eyes. Presence of high blood pressure also worsens the disease progress. Your mother should follow strict blood sugar level control. Doing HbA1c test will give a better evaluation of the control. Dietary changes need to be made and a renal diet needs to be followed. COnsultation with a diabetologist and nephrologist (kidney specialist) is important with regular monitoring of creatinine levels and urinary excretion of proteins.