Hi, I had gone through your question and understand your concerns. Prurigonodularis is a condition in which there will be excess growth of cells due to constant itching and continuous replacement of dead cells with new cells leads to nodule formation. It is a benign condition and may not transform into cancer. Treatment Of this is by - Use lots of moisturizer and take plenty of water. Anti allergen like Levocetrizin at night to decrease itching. Instead of steroid you can use other agents like-coal tar, calcitriol. some dermatological procedures like -cryotherapy,laser therapy,photo therapy will decrease the nodule size. There are some drugs to prevent the cell division like Methotrexate, isotretinoin. (take with doctor prescription only) consult a good dermatologist. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.