Hello and welcome to healthcaremagic Presence of pustular lesions in Psoriasis indicates that the disease is going to flare if has nt already. The presence of pustules is the sign of an unstable disease. Causes for a pustular flare are topical irritants like coal tar, anthralin, withdrawal of corticosteroids, infections like sore throat, stress, pregnancy, drugs etc I would suggest that you seek an appointment with your dermatologist. Drugs useful in pustular flare are oral immunosuppressives like either methotrexate OR cyclosporin OR oral retinoids e.g Acitretin, etc. They bring about rapid control of the disease. Oral antibiotics may also be started as a prophylactic measure for possible underlying infection. Topical applications of all possible irritant medications should be stopped and just bland emollients are allowed topically. An Oral antihistamine e.g cetrizine 10 mg would provide symptomatic relief from itching and burning sensation. Proper attention to fluid and electrolytes, temperature, pulse, Blood pressure is important during the flare Regards