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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suggest An Alternative Of Fragmin To Manage Blood Clotting

I have had 3 P/E s I am on 18000 units of Fragmin. I have cancer as well. I have been on Fragmin for well over a year. I consider my latest P/E as a fragmin failure. I will consult with my hematologist but I want to switch medications to better manage my clotting.
Mon, 8 Dec 2014
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Oncologist, Surgical,  's  Response
The reason for your P/E s could be dual. One it could be a failure of Fragmin, or an increase in your cancer load since the cancer is the probable cause of your increased coagulability state. If the cancer is increasing, then you need to step up whatever anti-cancer treatment you are taking, if that is possible. Otherwise, it might be worthwhile checking the dose of Fragmin. It is given at 1mcg per kg body weight. If the dose is correct then you might should switch to Tab Acitrom starting at 1mg per day, and checking your INR report after 1 week. thereafter you have to titrate the dose to keep the INR at between 2-2.5
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Suggest An Alternative Of Fragmin To Manage Blood Clotting

The reason for your P/E s could be dual. One it could be a failure of Fragmin, or an increase in your cancer load since the cancer is the probable cause of your increased coagulability state. If the cancer is increasing, then you need to step up whatever anti-cancer treatment you are taking, if that is possible. Otherwise, it might be worthwhile checking the dose of Fragmin. It is given at 1mcg per kg body weight. If the dose is correct then you might should switch to Tab Acitrom starting at 1mg per day, and checking your INR report after 1 week. thereafter you have to titrate the dose to keep the INR at between 2-2.5