Hi there, thanks for posting your query on this forum. Gutka addiction is equally dangerous as any other addiction as it contains carcinogens which lead to oral cancer if taken for many years. Taking gutka may cause symptoms like loss of sleep, loss of concentration, acidity, etc. Submucosal fibrosis is another important condition seen in gutka addicts where they are unable to open their mouth completely. Your concern is genuine but unless your husband and brother don t feel like stopping their habit nothing can be achieved. Irrespective of giving any medication or any counseling one cannot get rid of an addiction unless the person himself feels like giving up the habit. Regards, Dr. Kunal Lokare