Thank you for the query.
can always indicate a cancer. However it does not has to be stomach cancer
. As she has COPD I assume she smokes. Nausea and reflux indicates some digestive tract problems. And she is 53. Such age gives increased risk of colon cancer
He should have chest CT, abdominal CT (pancreas should be checked), upper GI endoscopy and colonoscopy
performed. Full blood work, CEA, CA 19.9 CA 125 should be done as well.
Hope this will help.