Hi, Isotretinoin works well for acne. It might lead to dryness or irritation over face. For the same you could use a mild moisturiser. I would strictly advise you not to use dermovate cream over face as it is a very potent steroid and can cause permanent harm to your face like increase in pimples, thinning of facial skin with visible blood vessels, irritation and burning sensation over skin etc. Continue with isotretinoin and consult your dermatologist if isotretinoin causes severe dryness. Hope that answers your query. Take care.