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Suffering from acne, pimples, rashes, blackheads and blemishes. Prescribed clindamycin phosphate and Benzoyl peroxide. Suggest to get clear skin?

Hi Doctor,

My name is Neha and am from India.I am 28 years old and struggling from acne from last 10-12 years.
I am using cymldaycin phosphate 1% and benzoly peroxide 4 % from last 2 years and it really helped to get clear skin.
Could you please tell me the skin effects if I use these medicine for long term.
As soon as I stop these medicines immediately i get pimples,rashes,blackheads and blemishes.
Please suggest me something,I really wanna get rid of my pimples forever and wants healthy skin.
Asked On : Mon, 8 Apr 2013
Answers:  1 Views:  247
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General & Family Physician 's  Response
Hi Neha, thanks for asking in Healthcare Magic.

Acne is hormonal. Under androgenic influence excess of sebum is produced in sebaceous glands and get infected by bacteria resulting in acne. But do not use any hormonal preparations for it as they can result in many side effects on long term use.

Benzyl peroxide is the most effective drug for acne. By liberating oxygen it kills the bacteria responsible for acne. It reduces the dark spots (black head) of acne. It reduces sebum production. Side effects are excessive dryness of skin, redness (erythema), swelling and contact dermatitis (allergy). How long you use it depends upon the degree of irritation it produces and the tolerance of your skin to it. You should discontinue if the side effects occur and persist.

Clindamycin is less effective than Benzyl peroxide. Effective mainly in infected acne. It should not be used on long term even as topical application. So you should stop Clindamycin. Other preparations like Adapalene and Retinoic acid are less effective than Benzyl peroxide.

Azelaic acid is a natural product and is used as topical application in acne. Though there is delayed response its effect is comparable to Benzyl peroxide. If you develop side effects to Benzyl peroxide, then you can switch over to Azelaic acid.

I hope this is useful.
Answered: Mon, 8 Apr 2013
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