Hi Shiva. Thanks for the detailed history. Make my life much better when I get a good summary of the problems and list of medications! People with advanced CKD have deficiency of production of erythropoietin
(EPO) and hence need it as injections. That along with replacement of any deficiency of the following - iron, Vitamin B12
should be sufficient. Your mother has something more than simple EPO deficiency. Kindly consult a haematologist ASAP. She will need more tests and a 'Bone Marrow' exam (if not already done) to diagnose the cause of severe anemia
. Best wishes.