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Specimen consists of irregular tissue, inflammatory cells are infiltrating the stroma gestational endometrium. Suggest?

the specimen consist of few irregular tissue fragments with an aggregate diameter of 3.5cm microscopic section shows sheets of decidual tissues made of plump ovoid to polygonal cells wih uniform centrally located nuclei abundant eosinophilic cytoplasm distict cellular borders The inflammatory cells are infiltrating the stroma gestational endometrium characterized by intricate gladular structures lined up bu plump cubiodal to columnar cells with abundant cytoplasm showing hobnailing character.
Asked On : Mon, 14 May 2012
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Pathologist and Microbiologist 's  Response
Hello and welcome to HCM,

The description that you have mentioned is the microscopic findings of endometrial biosy, curettings.
These microscopic findings suggest presence of decidua.
Decidua is the tissue which lines the uterine wall during pregnancy.
Thus, these findings indicate the presence of pregnancy.
The glandular structures are the endometrial glands which show Arias Stella reaction.
All these changes suggest a gestation/ pregnancy.
However, the pregnancy can be uterine or at some other site like fallopian tube.
the presence of villi is confirmatory of pregnancy.
These changes can also occur under the influence of hormones (progesterone).

Further you need to consult your gynaecologist for clinical correlation.
Thanks and take care.
Dr Shailja P Wahal

Answered: Wed, 24 Apr 2013
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