Hello,
From your question I come to know that your sister has been suffering from Ankle and knee joint pain and swelling since age of 18yrs till today, that is for 12 yrs and she also suffers from
colitis,
The picture points towards a a type of
arthritis (Joint Swelling) known as Seronegative
Spondyloarthropathy in which there is affection of joints and
colon both. Joints like knee/ankle/elbow or wrist swell up and pain and may resolve on its own or may not completely resolve. In colon, it may cause bleeding stools/ change in stool consistency/ frequency also.
This kind of arthritis is progressive and gradually worsens with age.
There are various kinds of blood tests like
HLA B27/
ESR etc. available to find exact type of arthritis.
I feel you should
consult a Rheumatologist for a correct diagnosis and who can give her a treatment which is far better than pain killers and work well too probably make her relieve her joint and colitis problems totally.
If the rheumatologist feels like than he may consult a orthropaedic surgeon like me or / and a gastroenterologist to have a complete treatment.
I hope this answers to your question and helps you and your sister.
God Bless you
Regards
Dr Merchant