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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Rheumatoid Arthritis, Taking Methotrexate With Remicade, Acute Kidney Failure, Stopped Medication. Is It Dangerous To Stop?

Hi, I usually take methotrexate with remicade to treat my rheumatoid arthritis but a month ago i was hospitalized with acute kidney failure and before i got out the kidney doctor told me that methotrexate was not good for the kidneys so i stopped taking it until i saw my specialist which is tomorrow... i have missed 4 injections approximately, is it dangerous to stop like that?
Fri, 21 Jun 2013
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General & Family Physician 's  Response
Hi,
Stopping methotrexate due to kidney failure is not a bad thing and no it wont affect you suddenly.
In rheumatoid arthritis there are a group medications we give to patients, we call them DMARDs.
As methotrexate, which is usually the first medication prescribed cannot be given, we shift to other drugs from that group, for example
infliximab
Cyclosporin A
leflunomide, etc

So dont worry and just inform your doctor about the whole situation.

I hope this answered your question.
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Rheumatoid Arthritis, Taking Methotrexate With Remicade, Acute Kidney Failure, Stopped Medication. Is It Dangerous To Stop?

Hi, Stopping methotrexate due to kidney failure is not a bad thing and no it wont affect you suddenly. In rheumatoid arthritis there are a group medications we give to patients, we call them DMARDs. As methotrexate, which is usually the first medication prescribed cannot be given, we shift to other drugs from that group, for example infliximab Cyclosporin A leflunomide, etc So dont worry and just inform your doctor about the whole situation. I hope this answered your question.