Hello, rizwan5125, If your mother has had this for over six months, the condition is chronic liver disease. She seems to have a very low platelet count and her Bilirubin levels are mildly elevated and her enzymes are moderately high. I am glad that her Hepatitis profile was negative especially for Type-B and Type-C. They are the bad ones. Type-A does not cause chronic liver disease. I am sure your mother never abused alcohol, so we can eliminate that as a cause. There are certain drugs (Prescription and non-prescrption) that can cause chronic liver damage. Ibuprofen, Naproxen, sulfa drugs, Tetracycline family of drugs can cause liver damage. Check all the medications she is on or has been taking. The other condition is Auto-Immune liver disease. She should be tested for these-Antinuclear Antibodies, Anti-smooth muscle antibodies, DNA &RNA antibodies, Serum complement level, Protein electrophoresis, R.A.Factor etc. Another condition common in women is Primary Biliary Cirrhosis. This may be associated with fatigue, itching of the skin, jaundice etc. Diagnosis is through Anti-mitochondrial antibodies and liver biopsy. You can discuss all these with her doctor and then appropriate treatment can be given. I wish her well.