Hi ! Good evening. I am Dr Shareef answering your query. The increase in her weight of 70 lbs is quite significant and along with the change in personality points towards a hormonal problem, which is more like a hypothyroidism
. In this condition, the individual gains weight without eating much, and goes into depression
and all kinds of personality and mood changes.the voice change is also likely due to hypo functioning of the thyroid gland where less thyroxine
is produced. Thyroxine is the hormone needed for normal functioning of all the systems of the body. The high blood pressure
and high cholesterol
also goes in favour of this .
Therefore, I would suggest you to go for a thyroid function test, and consult your family physician with the report, who may prescribe you the synthetic thyroxine available in the market as a replacement therapy, following which your mother may recover gradually.
I hope I have answered your query. Thanks for using heatlhcaremagic forum for your health query. Good luck.