Factor 5 runs in my husbands family. My 51 year old doctor has already had multiple blood clots, including a pulmonary thrombosis that almost killed her. Following a hysterectomy in her 40 s, she started gaining massive amounts of weight. Doctors chose to ignore her problems until she had the pt. After that, she was diagnosed with Cushings and had gastric bypass surgery. She has not been healthy for years and even had to have the gastric bypass surgery repeated and now has had surgery for a hernia. She cannot work but has been unable to get approval for any kind of financial help with her horrendous medical bills because her husband is employed. Is it possible the Factor 5 has anything to do with the problems she is having?