hi i am a patient of psoriasis as well as psoriatic arthiritis and was on a 10mg dose of methodroxate from last 2 years recently my disease flaired as told b my doc. rite now have acute pain in my knee and a little pain in my ankle .as advised my dose for methodroxate has been increased to 15mg per week and told to have 2ml depomedrol injections for 4 week (once a week)having depo for three week till now there has been no improvement in my knee and i feel weekness in the my partcular right leg in which i have pain please suggest what to do now?email id : YYYY@YYYY