Hello, I would be happy to help you with your question. I can find no evidence that there is any significant harm with this medication and its use in pregnancy. This does not mean that it is totally safe, but is considered okay to use if the benefits of the medication are felt to outweigh the risks of NOT treating. Base on your level of pain and how far along you are in pregnancy, you urgently need a consult with a General Surgeon to assess the need of removing your gallbladder. It will be a much more difficult issue to deal with later in pregnancy! I hope this helps. Please use the Premium service if you require more detail.