Hi Suresh. Based on the material posted by you from your wife's reports, I have to assume your wife has one kind of Macular dystrophy. Degeneration is generally referred to similar changes but due to age that occur in the macular area of the eye. There are a around 3 broad types of Macular dystrophy: autosomal dominant which means it manifests in more than one member of the family and an offspring has a 50% chance of getting the disease, autosomal recessive which shows in a patient who has normal parents but probably are related and X linked which has females who carry the diseased gene but is seen only in males. If your wife started having vision loss
in her teens, her parents or anyone else are not affected she probably has the recessive kind of dystrophy. This means that if you are not related and definitely normal without macular disease
, the chance of passing the disease to your child is non existent. That means your child will, in all probability be normal. however, no genetic testing
has been done on your wife and the report does not clarify what kind of Dystrophy she has. History leans strongly towards the recessive kind but if you like you may try genetic testing available in Hyderabad. There is no treatment or prevention possible for this disease as yet though there are promising genetic trials underway to isolate the mutant gene and treatment perhaps cannot be far behind.