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Pregnant, have severe vomiting, low appetite, prescribed Ondedom-4. Is this safe?

hello Dr. I am Raman currently living in India,I am 8 weeks pregnant, 24 years old. first pregnancy, a Dr. here prescribed me ONDEDOM-4 tablet for vomiting and nausea .. it contains Ondansetron Hydrochloride .. before this nothing worked for me, so far.. i have been sick and vomiting every single thing out since i was 5 weeks pregnant. apart from that i feel strong smells out of every thing and unable to eat my food. just wondering how safe this tablet is for my baby? need assurance.. thanks..
Asked On : Sun, 30 Sep 2012
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OBGYN 's  Response
Hello there..

The condition you have suggests that you are having hyperemesis gravidorum where in there is more than normal physiological vomitting associated with pregnancy.

Odansetron is 5HT receptor antagonist and is powerful antiemtic used in hyperemesis and other severe vomitting cases. It is safe in pregnancy. The only disadvantage is that it is bit costlier than other antiemetics available.
Since you are seeing a doctor personally , i hope you have got one ulltrasound done and blood test to rule out thyroid problem as excess vomitting can occur in pregnant females with thyroid disorders. Ultrasound is important to rule out a condition called gestational trophoblastic disease where there is abnormal placentation with no fetal tissue(baby) seen and is also associated with excess vomitting.
Nausea and vomiting usually peaks between 2 and 12 weeks of pregnancy and goes away by the second half of pregnancy. With proper identification of symptoms and careful follow-up, this condition rarely presents serious complications.

Some personal measures which might help you reduce yomitting are:
Small, frequent meals and eating dry foods such as crackers may help relieve uncomplicated nausea. Take dry items when you wake up and avoid fluids early morning because nausea is maximum while getting up in the morning.
You should drink plenty of fluids. Increase fluids during the times of the day when you feel the least nauseated. Seltzer, ginger ale, or other sparkling waters may be helpful.
Vitamin B6 (no more than 100 mg daily) has been shown to decrease the nausea in early pregnancy.
Medication to prevent nausea is reserved for cases where vomiting is persistent and severe enough to present potential risks to you and your unborn baby.
If it's mild, you should change your diet by eating more protein and complex carbohydrates, such as nuts, cheese and crackers, and milk. It's best to eat these foods in small portions, several times throughout the day. You should also avoid eating fatty foods, drink plenty of water, and get as much rest as possible.
You can also take antacids which will help reduce reflux and nausea.
Answered: Mon, 1 Oct 2012
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