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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Pregnant Done Elecrophoresis Test. Worried About Thalassemia

Hiiii, my wife is 17 week pregnant as on date. her hb electrophoresis resulsts shows:-
Hb A - 9.1
Hb F - 28.0
Hb S+D+G - 60.3
After watching the results, doctor advised me for the hb electrophoresis test. My results are normal. After that sickling test has been done for my wife and this result is negative. Please advise further. I am worring about thelessemia. Till now there is no history of any major illness or blood transfusions for my wife.
Mon, 20 May 2013
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OBGYN,  's  Response
Hello
thanks for your query.
Your wife has an abnormal hemoglobin pattern.
As you are not positive for thalessemia, at the most, your child would have a risk of being a carrier for this abnormal hemoglobin pattern.
And that too is not a certainty.
Please be reassured if your wife has no major clinical symptoms.
For best guidance regarding patterns of inheritance of hemoglobinopathies, please consult a Genetic counsellor.
All the best.
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Pregnant Done Elecrophoresis Test. Worried About Thalassemia

Hello thanks for your query. Your wife has an abnormal hemoglobin pattern. As you are not positive for thalessemia, at the most, your child would have a risk of being a carrier for this abnormal hemoglobin pattern. And that too is not a certainty. Please be reassured if your wife has no major clinical symptoms. For best guidance regarding patterns of inheritance of hemoglobinopathies, please consult a Genetic counsellor. All the best.