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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Positive HLA B27 Antigen, Have Intense Back Pain Throughout The Day. What Could Be The Treatment For Ankylosing Spondylosis?

I have recently tested positive for HLA B27 antigen , which was tested because of my back pain that has been going on for 4 years now. The pain is extreme after sleeping and the morning, and dull throughout the day. I just got an MRI and dont have an appointment to go over what the results meant for a month curious if someone could help me interpret what it says and to give opinion if I have anylosing spondylitis like I have suspected
Wed, 26 Sep 2012
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Internal Medicine Specialist,  's  Response
Hi,
Welcome to HCM
It is a test done to know genetic predisposition to certain rheumatological diseases called SSA(Seronegative spondyloarthropathy) one of these is Ankylosing Spondylitis(AS).
In general about 5% may test positive for HLA B27 it association with Ankylosing Spondylitis is > 85% and if you are already having backache for last 4 years it is quite possible to have some association.
MRI will be good to know extent of damage and any compression on neural roots if any.
Please see your Rheumatologist and take physiotherapy as advised
Good luck to you


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Positive HLA B27 Antigen, Have Intense Back Pain Throughout The Day. What Could Be The Treatment For Ankylosing Spondylosis?

Hi, Welcome to HCM It is a test done to know genetic predisposition to certain rheumatological diseases called SSA(Seronegative spondyloarthropathy) one of these is Ankylosing Spondylitis(AS). In general about 5% may test positive for HLA B27 it association with Ankylosing Spondylitis is 85% and if you are already having backache for last 4 years it is quite possible to have some association. MRI will be good to know extent of damage and any compression on neural roots if any. Please see your Rheumatologist and take physiotherapy as advised Good luck to you