Metformin can be safely used in renal transplant recipients as per studies conducted. It can lead to hyperglycemia
in the presence of steroid like Prednisone
and hence needs to be monitored carefully. In PCOD, it is mostly used to induce spontaneous ovulation by correcting the associated Insulin resistance
. For the treatment of ovarian cysts, other possible alternate treatments include use of combination oral pills, laparoscopic cyst
puncture etc. Hope this helps.