Tissue plasminogen activator
, or streptokinase IV, Is given to dissolve blood clots
that have formed in the coronary artery. Side effects bleeding,hypotension
, allergic reactions, reperfusion cardiac arrhythmia's. Contraindications recent surgery,injury, Gi bleeding. At the same time give oxygen, nitro, morphine
and gravol. Keep the K-basin handy because nausea and vomiting will soon follow.TPA and Streptokinase are classified as thrombolytic agents.