Thanks for writing to us with your health concern.
Generally speaking, Metformin is not associated with any kind of changes in the sizes of the breasts.
With PCOS, irregular cycles are the norm.
More often than not, there are prolonged periods
of amenorrhoea.Weight loss
is a must, the loss you have had is commendable, but more is needed.
Please have a complete workup for PCOS.
This will include a pelvic ultrasound scan .
Also, hormonal levels - FSH, LH,TSH, Prolactin, OGTT, DHEAS, Serum free testosterone
, Lipid Profile
Next, take a pregnancy test to rule out pregnancy conclusively
WIth PCOS, ovulation is erratic and hence it is better to rely on a blood pregnancy test.
Yes, since ovulation is erratic, you can conceive even during supposed periods of amenorrhoea.
Take regular folic acid
supplements as you are TTC.
All the best
Please feel free to discuss further.