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PCOS, hypothyoid, obese, suffering from peripheral neuralgia, trying to concieve. Having vomitting, nausea, bloating. Missed periods. Pregnancy tests negative. Suggestions?

Hi, I am a thirty year old woman with PCOS , on Metformin for that, and Levothyroxine for hypothyroidism . My husband and I have been trying to conceive for years, and I struggle with obesity . Things are further complicated by the fact that I have some neurological problems too - peripheral neuralgia - according to the neurologist , which is untreated (we re waiting and seeing ) but makes it hard to walk on occasion, and gives me numbness and tingling in lower legs, and occasional weakness and balance issues. (This of course makes it even harder to lose weight.) Anyway, my current problem is that I have not had any bleeding/ period for nearly 9 weeks. LMP- 13th Oct. I have felt nauseous, had a super strong sense of smell and a nasty taste in my mouth for a couple of weeks, off and on. Also been a bit bloated and noticed more I ve been more gassy than usual. BMs have been fine and pretty regular. Today my nausea has intensified and I ve thrown up over ten times - there is nothing left to throw up. I ve only managed a tiny sip of water all day without vomiting. Today I also have mild lower abdominal ache and twinges every now and then. The nausea is intense and pretty much constant. This morning I had a tiny tiny bit of bright red spotting when I first wiped, just after I woke up, but nothing since. No other bleeding other than a tiny bit of spotting about 20 or so days ago... I ve done two Clear Blue pregnancy tests, both of which were negative (one two week ago or so, and one this morning). I know PCOS sufferers often have missed periods, but although my cycles often seem to be anovulatory, for the last two years I have been charting (at least keeping a note of cycle lengths). My cycles have been a bit erratic, varying between 20 and 34 days, but I have had bleeding every 28 days on average. I ve not gone this long (62 days) without a period since I was a teenager. Before starting Metformin my problem was too frequent and heavy bleeding. I understand that negative tests at this stage would usually confirm absence of pregnancy, but my mother and others I have known with similar hormonal issues to me have not tested positive in urine or blood tests until late into pregnancy. I also failed to get a positive test result before I (almost definitely) had an early miscarriage at about 5 1/2 weeks in 2010. Have you encountered this in others with PCOS? If I am not pregnant, then what else could be causing this extreme nausea and vomiting and other symptoms? Also, if it is the PCOS/ a cyst then what has caused lack of menstruation rather than regular estrogen-bleeds? Nothing else in my lifestyle has changed and I am not really stressed - just feeling ill. What causes some women with PCOS who are anovulatory to bleed a lot, and others not at all? It is all very confusing. I would really appreciate your help in getting to the bottom of all this. Thanks for your time.
Asked On : Sun, 16 Dec 2012
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