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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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On Crestor Due To High Cholesterol. Elevated SGPT. Medication?

Good morning....I had blood work in November. Cholesterol of 247 led me to be put on crestor. Everything else was normal. Jan repeated blood to find everything still normal including a drop to 177 in cholesterol. My concern now is is my April blood work now shows cholesterol 133 / great but my ot went from 20 to 55 and my sgpt went from 28 to 171… I also just started adipex 3 weeks ago and I'm on losartan htc.
Mon, 22 Apr 2013
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Orthopaedic Surgeon,  's  Response
Crestor may have induced liver enzyme increase. Ask your Doc.if its dosage could be rduced.Other side effect is pain in muscles. optimum dose is 5- to 20 mg single dose daily.
What was your triglycerideand HDL LDL VLDL cholesterol? Total cholesterol247 doesn't sem to be so high, if crestor is being given,reduction to 10 mg will give same benefit as higher dose as recent study say.,however ask your doc.again.
Get complete Lipid profile, Liver function tests before you consult
I am sure your doc.must have advised low fat diet to you,exercise also.
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General Surgeon,  Dr. Dr. Ivan Romich's  Response
hi and welcome to HCM.
It is known that statins including Crestor can casue elevated liver enzymes and this probably happened in your case. YOu should stop taking crestor for 2-3 weeks and see is SGPT gonna improve or there is some other cause for liver damage.Also do liver ultrasounds and viral markers. Adipex side effects are still nor investigated, but try to lose weight naturaly if you can. Also dietary changes would improve you lipidogram.
Wish you good health.
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On Crestor Due To High Cholesterol. Elevated SGPT. Medication?

Crestor may have induced liver enzyme increase. Ask your Doc.if its dosage could be rduced.Other side effect is pain in muscles. optimum dose is 5- to 20 mg single dose daily. What was your triglycerideand HDL LDL VLDL cholesterol? Total cholesterol247 doesn t sem to be so high, if crestor is being given,reduction to 10 mg will give same benefit as higher dose as recent study say.,however ask your doc.again. Get complete Lipid profile, Liver function tests before you consult I am sure your doc.must have advised low fat diet to you,exercise also.