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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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On Loxapine And Paroxetine. Any Unique Quality Of Loxapine As Antipsychotic Drug?

I am on Loxapine 10 mg and paroxetine 12.5 mg. Is loxapine a unique antipsychotic since it does not belong to phenothiazine or thioxanthene class? In which way loxapine is superior to other antipsychotic drugs chemically and in side effects? Since it is not mostly prescribed by psychiatrists in India I would like to know the unique quality of the drug in controlling psychosis.Can paroxetine act as a mood stabilizer? can it control anger?
Tue, 11 Jun 2013
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General & Family Physician,  's  Response
The exact mode of action of loxapine has not been established,but a significant decrease in aggressive behaviour has been noted in animal and human studies.The drug can be of use in Schizophrenia.Taking the drug with Paroxetine with which it has a moderate interaction is not a good idea because it causes drowsiness,impaired thinking and judgement,loss of concentration and dizziness.
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On Loxapine And Paroxetine. Any Unique Quality Of Loxapine As Antipsychotic Drug?

The exact mode of action of loxapine has not been established,but a significant decrease in aggressive behaviour has been noted in animal and human studies.The drug can be of use in Schizophrenia.Taking the drug with Paroxetine with which it has a moderate interaction is not a good idea because it causes drowsiness,impaired thinking and judgement,loss of concentration and dizziness.