Thanks for posting your query.
Increased ESR is a sign of chronic disease running in your body and as you have history of weight loss
, you should go for thorough check up.
Kindly mention other symptoms if you have.
You should also consult with physician and go for following investigations: CBC, CRP, thyroid
profile, renal function test, chest x ray
imaging as preliminary test.
Dr. Mayank Bhargava