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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Need Help To Understand Lab Results For Chrohns Disease. Do I Have The Disease?

Lab results for crohns. understanding results? Please help me understand my crohns disease lab test results. Negative : = 20.0 Equivocal : 20.1- 24.9 Weak Positive : 25.0- 34.9 Positive: = 35.0 Clinical Group: ASCA IgA Pos. ASCA IgG Pos. ASCA IgA or IgG Pos. ASCA IgA and IgG Pos. Crohns Disease : 49% 74.4% 76.2% 47.6% Ulcerative Colitis : 1.9% 14.2% 14.6% 1.3% Healthy Controls : 1.4% 1.4% 5.6% 0.0% do i have crohns or not??
Mon, 17 Dec 2012
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Gastroenterologist,  's  Response
Hello, christina.vandian,
From what you have mentioned about your results,
I understand that your ASCA IgA and ASCA IgG were both
positive.
pANCA is another antibody test that is more common with
ulcerative colitis.
ASCA IgG and IgA are more common with Crohn's (40-50 % ).
If you have findings on your small bowel x-rays or endoscopy
suggestive of Crohn's and these lab tests are positive, it is
highly likely you have thie condition.
Along with this, if you have a family member that had either
ulcerative colitis or Crohn's , your risk goes up.
There are other antibody tests as well, such as
Anti-CBir1 (50 % in Crohn's)
Anti-Omp C (Associated with rapid progression of Crohn's)
Anti-I-2.
You can discuss these with your gastroenterologist.
I wish you well.
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Need Help To Understand Lab Results For Chrohns Disease. Do I Have The Disease?

Hello, christina.vandian, From what you have mentioned about your results, I understand that your ASCA IgA and ASCA IgG were both positive. pANCA is another antibody test that is more common with ulcerative colitis. ASCA IgG and IgA are more common with Crohn s (40-50 % ). If you have findings on your small bowel x-rays or endoscopy suggestive of Crohn s and these lab tests are positive, it is highly likely you have thie condition. Along with this, if you have a family member that had either ulcerative colitis or Crohn s , your risk goes up. There are other antibody tests as well, such as Anti-CBir1 (50 % in Crohn s) Anti-Omp C (Associated with rapid progression of Crohn s) Anti-I-2. You can discuss these with your gastroenterologist. I wish you well.