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From above description, It appear that your brother is having adjustment problem after the broken relationship with her female friend. Adjustment problem usually resolved with in 1-2 months of stressors on its own.
If problem is prolonged or severe then, for treatment, you can visit specialist like psychiatrist
. Cognitive behavior therapy from trained therapist also help in these cases.
I hope this information has been both informative and helpful for you.
Wish you Good Health.
Dr. Ashish Mittal