Welcome and thanks for posting your query to HCM.
As per your query your moth is suffering from scleroderma
and she is on certain medication and feeling fatigue
The abnormal feeling is related to the medicine Methotrexate
. There is a feeling of moderated to severe nausea
, fatigue and aversion for food in the initial course of therapy with methotrexate. So the problem is that in oral form it causes nausea.
For reducing these side effects your mother can take it in following manner :
1.Take it after meals
2. Divide the dose into small parts in a week ( say for 15 mg can be taken three days/ week)
3. Take it at night time when you are sleeping
4.She can also be shifted to the injectable form which considered best if you are not able to take it orally.
For the itching part she can take antihistamine drugs under medical supervision. Despite above measures if she is not getting relief then you can talk to the treating doctor for further guidance.
With best health wishes for your mother,
Dr Sanjay K Kanodia