Thank you for posting your query.
It is unfortunate that your wife has suffered paralysis
of both legs, and no cause has been identified so far.
The most likely cause in this case is acute transverse myelitis
, which is usually caused by viral infections of the spinal cord
. MRI of spine may be normal initially, but findings appear later on when the MRI is repeated.
Other tests that can help are lumbar puncture
and evoked potential studies- both somatosensory and tibial.
A course of steroid therapy for 3-5 days is effective along with good physiotherapy
I hope it is helpful. I would be pleased to answer any more queries.
Dr Sudhir Kumar MD DM (Neurology)
Senior Consultant Neurologist