Hello and welcome to HCM
The history given by you suggests that your wife has spine tuberculosis which has spread to brain/ meninges
The tubercular infection
of the lungs is highly infectious and it spreads to others via fomites.
In cases associated with sputum production are also very infectious.
In contrast, tuberculosis of other sites like spine (bone) and brain/ meninges is not as infectious as pulmonary tuberculosis
Treatment with anti-tubercular drugs is required to render the infected person non-infectious. A minimum of one month treatment is needed for this.
To be on the safer side start the treatment and after continue it for 2 weeks to 4 weeks. try to avoid sexual contact for this period.
Once your wife responds well to anti-tubercular drugs (i.e. has no side effects), there is no risk of spread of infection.
Thanks and take care
Dr Shailja P Wahal