1. ME (mitochondrial encephalopathy
), L (lactic Acidosis
), S (stroke like episodes) affects muscle and nervous system, reason of dementia and loss of muscle function.
2. There have been no controlled studies on long-term aids of dietary manipulations, but the below supplements have presented some promise and have offered hope to MELAS individuals.
i. CoQ10 has been helpful.
ii. Riboflavin has been described as improving the patient functioning.
iii. L-arginine has been administrated during the serious as well as the interictal periods and might represent a probable new management for this syndrome to diminish brain damage
because of diminished vasodilation
in intracerebral arteries owing to nitric oxide reduction.
3. There is currently no known treatment for the underlying disease which is usually progressive and fatal. Individuals are managed according to what areas of the body are affected at any particular time.