Hi, thanks for writing to HCM. The fact that your treating doctor has prescribed cartigen duo tablets indicates that you have degenerative changes in your knee joint. The cause for mild knee effusion is also the degeneration process. The management of osteoarthritis is as follows - * PHYSICAL THERAPY : The mainstay of treatment in the early case is physical therapy, which should be directed at maintaining joint mobility and improving muscle strength. Other measures, such as massage and the application of warmth, may reduce pain. * LOAD REDUCTION : Protecting the joint from excessive load may slow down the rate of cartilage loss. It is also effective in relieving pain. Weight reduction for obese patients, wearing shock-absorbing shoes, avoiding activities like climbing stairs and using a walking stick are worthwhile. * ANALGESIC MEDICATION : Simple over the counter medications like acetaminophen is sufficient in most cases. If this fails to control pain, a non-steroidal anti-inflammatory drug may be better. * VISCOSUPPLEMENTATION: Hyaluronic acid injections given into the joint in prescribed dosages will give good short term relief in selected cases and helps in postponing total knee replacement surgery atleast for a year or two. Hope this information is helpful. Good day