HI,Transitional cell carcinoma
(TCC) can be very difficult to treat. Treatment for localized stage TCC is surgical resection of the tumor
, but recurrence is common. Some patients are given mitomycin
(which is a chemotherapeutic drug) into the bladder either as a one-off dose in the immediate post operative period (within 24 hrs) or a few weeks after the surgery as a six dose regimen.
Localized/ early TCC can also be treated with infusions of BCG
into the bladder. These are given weekly for either 6 weeks (induction course) or 3weeks(maintenance / booster dose). Side effects include a small chance of developing systemic Tuberculosis
(T.B.) or the patient becoming sensitized to the BCG causing severe intolerance and a possible reduction in bladder volume due to scarring.thankyou.