Thanks for your query.
is an anti-histaminic which will certainly reduce itching and can be taken along with warfarin.
Secondly, long-term Tramadol does cause lot of acidity, including gastro esophageal reflux disease
(as in your case). To minimize this side effect, take Tramadol with meals; regular anti-acid drugs, such as omeprazole
Consult your doctor who knows what would be best for you.
Dr. Rakesh Karanwal