Welcome to HCM,
It seems that your wife has got some allergy
to something bye external or internal things.
You find out the allergen by which this allergy occurs.
It may be due to cosmetics,clothes,change of soap,using some deodorant or perfume.
Synthetic clothes also may produce this allergy,
Eating some veggies or fruits also can cause.
Having warm infestation i.e.thread warm,round warm etc.
Mean while she can take anti allergy like Cetrizine
Ok and bye..